Hyphenated Techniques (LC-NMR-MS, HPLC-ESI-MS, MC-ICP-MS, HPLC-ICP-MS, UPLC-Q-TOF/MS)
A Hyphenated technique is combination or coupling of two different analytical techniques with the help of proper interface.Chromatography - Produces pure or nearly pure fractions of chemical components in a mixture. Spectroscopy – Produces selective information for identification using standards or library spectra. The hyphenated technique is developed from the coupling of a separation technique and an online spectroscopic detection technology. The number of existing techniques has been combined to expand the utility.