CPD Accredited International Conference on Mass Spectrometry and Proteomics

Dublin, Ireland

June 25-27, 2018

It is a great pleasure and an honour to extend our warm invitation to attend the "International Conference on Mass Spectrometry and Proteomics”, on June 25-27, 2018 in Dublin, Ireland, which includes prompt keynote presentations, oral talks, poster presentations and exhibitions. This conference brings together individuals who are interested in fields of mass spectrometry, proteomics, chromatography and analytical chemistry and approaching towards the conference gives best platform to explore the ideas and issues concerned to relevant topic and generate solutions.

This unites all the participants from across the globe. It is a platform to share their experience and their ideas for research work results to implement in further research work. As scientists, and other researchers all fascinated by the study of the global use of mass spectrometry. We are particularly concerned about understanding the uses of mass spectrometry in the field of chemistry and analytical science. We welcome you to our site to join with us. At this site, you can learn about membership in the society, the society journal, our newsletter and conferences.

Why to attend???

Speaker benefits at Mass Spectrometry Congress 2018:

o   Opportunity to Chair/Co-chair a session of your interest
Library of Abstracts which brings worldwide exposure to the researchers and speakers participate in our conferences.

o   Speaker and Abstract pages created in Google on your name would get worldwide acknowledgment to your research profile

o   Opportunity to get sponsorship for your projects

o   Opportunity to moderate the conference

o   Career Guidance Workshops to the Graduates, Doctorates and Post-Doctoral Fellows

o   Accepted Abstracts will be published in respective supporting journals, each abstract will be labeled with a DOI provided by Cross Ref.

o   Speaker will be felicitated with Certificate

o   Best Poster Competitions and Young Researcher Competitions

o   B2B meetings

o   All attendees can avail 21 CPD Credits (Continuing Professional Development) 

o   Certificate Accreditation by the International Organizing Committee (IOCM)

o   Abstracts will be published in conference souvenir & international journals

Allied Academies invites all the participants from all over the world to attend "International Conference on Mass Spectrometry and Proteomics”, on June 25-27, 2018 in Dublin, Ireland which includes prompt keynote presentations, oral talks, poster presentations, sponsors and exhibitions.

Allied Academies is a scientific association known for promoting scientific temperament and has been performing very well in Business and Management and is a perfect platform for our readers. It is established in the year 1997. The main motto is making the information on science and technology. It is a specialized medical and science publisher that operates in collaboration with the association and societies.  This publishing house has been built on the base of esteemed academic and research institutions including The College of Audiologists and Speech Language Pathologists of Ontario (CASLPO), The Association for Public Safety Communications Officials of Canada (APCO), The Canadian Vascular Access Association (CVAA), and The Canadian Society of Internal Medicine (CSIM).

Mass Spectrometry Congress aims to bring together the prominent researchers, academic scientists, and research scholars to exchange and share their experiences on all aspects of Mass Spectrometry. It is also an interdisciplinary platform for researchers, practitioners and educators to present and discuss the most recent advances, trends, and concerns as well as practical challenges and solutions adopted in the fields of Mass Spectrometry and Proteomics. 

Track 1: Fundamentals in Mass Spectrometry
As per Fundamentals of Mass Spectrometry, Mass spectrometry is an analytical tool used for measuring the molecular mass of a sample. Ionization is the atom or molecule is ionized by knocking one or more electrons off to give a positive ion. This is true even for things which you would normally expect to form negative ions or never form ions at all. Most mass spectrometers work with positive ions. New Ion activation methods for tandem mass spectrometry; this is followed by tandem mass spectrometry, which implies that the activation of ions is distinct from the laboratory research, and that the precursor and product ions are both characterized independently by their mass/charge ratios.

Track 2: Applications of Mass Spectrometry
Application of Mass Spectrometry includes the ion and weights separation. The samples are usually introduced through a heated batch inlet, heated direct insertion probe, or a gas chromatograph. Ionization mass spectrometry (ESI-MS) which has become an increasingly important technique in the clinical laboratory for structural study or quantitative measurement of metabolites in a complex biological sample. Mass spectrometry is an analytical meth ods with high specificity and a growing presence in laboratory medicine. Various types of mass spectrometers are being used in an increasing number of clinical laboratories around the world, and, as a result, significant improvements in assay performance are occurring rapidly in areas such as toxicology, endocrinology, and biochemicalmarkers. This review serves as a basic introduction to mass spectrometry, its uses, and associated challenges in the clinical laboratory and ends with a brief discussion of newer methods with the greatest potential for Clinical and Diagnostic Research.

Track 3: New Approaches in Mass Spectrometry
The search of metabolites which are present in biological samples and the comparison between different samples allow the construction of certain biochemical patterns. The mass spectrometry (MS) methodology applied to the analysis of biological samples makes it possible for the identification of many metabolites. The 100 chromatograms were concatenated in a vector. Identification of unknown peaks in gas chromatography (GC/MS)-based discovery metabolomics is challenging, and remains necessary to permit discovery of novel or unexpected metabolites that may allergic diseases  processes and/or further our understanding of how genotypes relate to phenotypes. Here, we introduce two new technologies and an advances in pharmaceutical analyticalmethods that can facilitate the identification of unknown peaks. First, we report on a GC/Quadrupole-Orbitrap mass spectrometer that provides high mass accuracy, high resolution, and high sensitivity analyte detection.
 
Track 4: Mass Spectrometry in Pharmaceutical Analysis
Mass spectrometry is one of the important tools in the analysis of pharmaceuticals. It is a technique used to measure the characteristic of a sample, likely to be availability of new instrumentations and ionization techniques which used to solve bio analytical problems.  It consists of both qualitative and quantitative aspects. And it is associated with drug discovery and drug development process. 

Track 5: Recent Advances and Development in Mass Spectrometry
New mass spectrometry (MS) methods, collectively known as data independent analysis and hyperreaction monitoring, have recently emerged. The analysis of peptides generated by proteolytic digestion of proteins, known as bottom-up proteomics, serves as the basis for many of the protein research undertaken by mass spectrometry (MS) laboratories. Discovery-based or shotgun proteomics employs data-dependent acquisition (DDA).  The selection of the SRM transitions is normally calculated on the basis of the data acquired previously by product ion scanning, repository data in the public databases or based on a series of empirical rules predicting the Enzyme structure sites.

Track 6: Mass Spectrometry in Toxicology
Toxicology is aimed to correlate the quantitative and qualitative relationship between the poison and their behavioural effects. So as it focus on elucidation of the mechanisms of actions of poisons, Mass spectroscopy has become important analytical technique used in the toxicological analysis of drugs, poisons, and their metabolites of both. Mass spectroscopy applies all fields of toxicology, such as environmental, clinical, and forensic toxicology.

Track 7: Mass spectrometry Imaging
Mass spectrometry imaging is a technique used in mass spectrometry to visualize the spatialdistribution of chemical compositions e.g. compounds, biomarker, metabolites, peptides or proteins by their molecular masses. Although widely used traditional methodologies like radiochemistry and immunohistochemistry achieve the same goal as MSI, they are limited in their abilities to analyse multiple samples at once, and can prove to be lacking if researchers do not have prior knowledge of the samples being studied.

Track 8: IonizationTechniques
There are many types of ionization techniques are used in mass spectrometry methods. The classic methods that most chemists are familiar with are electron impact (EI) and FastAtom Bombardment (FAB). These techniques are not used much with modern mass spectrometry except EI for environmental work using GC-MS. Electrosprayionization (ESI) - ESI is the ionization technique that has become the most popular ionization technique. The electrospray is created by putting a high voltage on a flow of liquid at atmospheric pressure, sometimes this is assisted by a concurrent flow of gas.

Track 9: Mass Spectrometry in Analytical Science
Mass spectrometry is a way to measure the mass of ions which are electrically charged species and derived from atoms or molecules. This technique is used to explore the chemical molecules. And used to know the fundamental atomic and molecular processes as a technique. It helps to control the process in chemical and biological industries, diagnosis diseases, discover new drugs, and protect the environment.

Track 10: Mass Spectrometry Configurations and Separation Techniques
Mass Spectrometry Configurations and Techniques is regards to Mass Spectrometry configuration of source, analyzer, and detector becomes conventional in practice, often a compound acronym arises to designate it, and the compound acronym may be better known among nonspectrometrists than the component acronyms. The Mass Spectrometry instrument consists of three major components those are Ion Source: For producing gaseous ions from the substance being studied; Analyzer: For resolving the ions into their characteristics mass components according to their mass-to-charge ratio and Detector System: For detecting the ions and recording the relative abundance of each of the resolved ionic species. Charged ions of various sizes are generated on the sample slide and MALDI is the abbreviation for "Matrix Assisted Laser Desorption/Ionization.

Track 11: Chromatography
Liquid chromatography-mass spectrometry analysis of small molecules from biofluids requires sensitive and robust assays. Because of the very complex nature of many biological samples, efficient sample preparation protocols to remove unwanted components and to selectively extract the compounds of interest are an essential part of almost every bioanalytical workflow. 

Track 12: High Performance Liquid Chromatography (HPLC)
High-performance liquid chromatography (HPLC) is a separation technique that can be used for the analysis of organic molecules and ions. HPLC is based on mechanisms of adsorption, partition and ion exchange, depending on the type of stationary phase used. HPLC involves a solid stationary phase, normally packed inside a stainless-steel column, and a liquid mobile phase. Separation of the components of a solution results from the difference in the relative distribution ratios of the solutes between the two phases. HPLC can be used to assess the purity and/or determine the content of many pharmaceutical bioprocessing substances. It can also be used to determine enantiomeric composition, using suitably modified mobile phases or chiral stationary phases. It is a very powerfultechnique that often requires non-polar solvents. Due to safety and environmental concerns this mode is used mostly as an analytical technique and not for process applications.

Track 13: HyphenatedTechniques (LC-NMR-MS, HPLC-ESI-MS, MC-ICP-MS, HPLC-ICP-MS, UPLC-Q-TOF/MS)
 A Hyphenated technique is combination or coupling of two different analytical techniques with the help of proper interface.Chromatography - Produces pure or nearly pure fractions of chemical components in a mixture. Spectroscopy – Produces selective information for identification using standards or library spectra. The hyphenated technique is developed from the coupling of a separation technique and an online spectroscopic detection technology. The number of existing techniques has been combined to expand the utility.

Track 14: Mass spectrometry in environmental analysis
Liquid chromatography (LC) is becoming a popular separation technique in environmental analysis. Most LC nowadays is High Performance Liquid Chromatography (HPLC) which uses small particles packed together at high pressure. While gas chromatography still remains popular in environmental analysis, particularly for volatile and non-polar compounds, it does not lend itself to analyzing compounds which are polar, non-volatile, thermolabile or have a high molecular weight. For such compounds, LC is better. LC-MS is the most popular

Track 15: Maintenance,Troubleshooting, Data Analysis and Experimentation in Mass Spectrometry
Mass spectrometry experiment (ms) is a high-throughput experimental method that characterizes molecules by their mass-to-charge ratio. the ms is composed of sample preparation, molecular ionization, detection, and instrumentation analysisprocesses. ms is beneficial in that it is generally fast, requires a small amount of sample, and provides high accuracy measurements. If the foreline pump is not maintained, the oil may become so contaminated that the  optimum pumping is no longer possible.  initially, gas transport and metabolism ballasting may clean the oil.  if the  oil has become discoloured then it should be changed according to the pump  manufacturers’ maintenance manual.  when rotary pumps are used to pump away conflict resolution, the solvent can  become dissolved in the oil causing an increase in backing line pressure.

Track 16: Proteomics
Proteomics has become an essential tool for understanding biological systems processes at the molecular level. Plant Proteomics publishes novel and significant research in the field of proteomics that examine the dynamics, functions, and interactions of proteins from plant systems. Nutritional proteomics is quickly developing to utilize little atom substance profiling to bolster incorporation of eating regimen and sustenance in complex biosystems research. Nutrigenomics is a branch of nutritional genomics and is the study of the effects of foods and food constituents on gene expression.

Track 17: Mass Spectrometry in Proteome Research
Mass spectrometry (MS) - based proteomics allows the sensitive and accurate quantification of almost complete proteomes of complex biological fluids and tissues. At the moment, however, the routinely usage of MS-based proteomics is prevented and complicated by the very complex work flow comprising sample preparation, chromatography, MS measurement followed by data processing and evaluation. The new technologies, products and assays developed by Precision Proteomics could help enabling and establishing mass spectrometry (MS) - based proteomics in academic and pharmaceutical research as well as in clinical diagnostics.

Track 18: Proteomics and its applications
Proteomics has become an essential tool for understanding biological systems processes at the molecular level. Plant Proteomics publishes novel and significant research in the field of proteomics that examine the dynamics, functions, and interactions of proteins from plant systems. Nutritional proteomics is quickly developing to utilize little atom substance profiling to bolster incorporation of eating regimen and sustenance in complex biosystems research. Nutrigenomics is a branch of nutritional genomics and is the study of the effects of foods and food constituents on gene expression. Foodomics has been recently defined as a new discipline that studies food and nutrition domains through the application of advanced technologies in which MS techniques are considered indispensable.

Track 19: Spectroscopy
Spectroscopy is the study of the interaction between matter and electromagnetic radiation. Historically, spectroscopyoriginated through the study of visible light dispersed according to its wavelength, by a prism. Later the concept was expanded greatly to include any interaction with radiative energy as a function of its wavelength or frequency. Spectroscopic data is often represented by an emission spectrum, a plot of the response of interest as a function of wavelength or frequency.

Track 20: Mass Spectrometry in Metabolomics and Lipidomics
Data analysis for metabolomics typically consists of feature extraction, statistical analysis, compound identification and biological pathway analysis. The Thermo Scientific™ suite of metabolomics software products allows you to quickly transform complex data into useful results. HRAM Orbitrap LC-MS is a widely adopted technique for lipidomics analyses. Together with a comprehensive database and library that provides accurate lipid identification, this technology enables relative as well as absolute quantitation from biological samples. Mass spectrometry (MS) is a central technology in Metabolomics due to its very high sensitivity and selectivity. Combined with a separation step before the MS-detection (e.g. gas chromatography (GC), liquid chromatography (LC), convergence chromatography (UPC2), or capillary electrophoresis (CE)).

Track 21: Nuclear Magnetic Resonance (NMR) Spectroscopy
Nuclear Magnetic Resonance (NMR) spectroscopy is an analytical chemistry technique used in quality control and reserach for determining the content andpurity of a sample as well as its molecular structure. For example, NMR can quantitatively analyze mixtures containing known compounds. For unknown compounds, NMR can either be used to match against spectral libraries or to infer the basic structure directly. Once the basic structure is known, NMR can be used to determine molecular conformation in solution as well as studying physical properties at the molecular level such as conformational exchange, phase changes, solubility, and diffusion. In order to achieve the desired results, a variety of NMR techniques are available.

Track 22: Clinical application of mass spectrometry
Clinical laboratories use the MS technology for disease screening, diagnosis of disease and metabolic disorders, monitoring of drug therapy, identifying drug toxicity and poisoning, and discovering new biomarkers. Therapeutic monitoring of immunosuppressant drugs using MS is well established. Limitations of immunoassays such as nonspecific binding of the antibody and cross-reactivity with metabolites that often result in overestimation have made the more accurate LC/MS/MS methodologies the assays of choice. LC/ MS/MS has become the standard for assay of steroid hormones for diagnosis of endocrine disorders. Vitamin D analysis by LC/MS/MS is widely used in the clinical laboratory today. Whereas immunoassays are unable to distinguish between 25-hydroxy vitamins D2 and D3, the LC/MS methodologies are able to measure these leves.
 
 

Market Analysis Report of Mass Spectrometry :

On the basis of technology, the mass spectrometry market is broadly segmented into single mass spectrometry, hybrid mass spectrometry, and other mass spectrometry technologies (magnetic sector, inductively coupled plasma mass spectrometry). In 2017, the hybrid mass spectrometry segment is expected to account for the largest share of this market. The extensive applications of hybrid mass spectrometers coupled with the technological advancements in mass spectrometry are driving the growth of this segment. Based on application, the mass spectrometry market is further segmented into pharmaceutical application, biotech application, environmental testing, food and beverage testing, petrochemical applications, and other applications. In 2017, the pharmaceutical applications segment is expected to account for the largest share. Extensive use of mass spectrometry technologies at various stages of drug development processes and increase in R&D investments by pharmaceutical industries are driving the growth of the market. North America accounted for the largest share of the mass spectrometry market in 2016, followed by Europe. High usage of mass spectrometry in the pharmaceutical sector, growing funding to favour mass spectroometry market in the US, high petrol and natural gas production, growing biopharmaceuticals and biotechnology research & development and funding for innovation based projects in Canada is expected to drive market during the forecast period. Factors such as availability of funds for research, growing cosmetics industry in Germany, growing food safety concerns and increased investments for pharmaceuticals in the UK, favorable scenario of biotechnology and pharmaceutical industry in Italy, company’s expansion in France and strong food and beverage industry in Spain are driving factors of  the European mass spectrometry market.

These are top suppliers of Mass Spectrometry:

Agilent Technologies (US), Thermo Fisher Scientific (US), Waters Corporation (US), and SCIEX (Subsidiary of Danaher) (US) are the key players in the mass spectrometry market. Other players involved in this market are Bruker (US), PerkinElmer (US), JEOL (Japan), Analytik Jena (Germany), Hiden Analytical (UK), Rigaku (Japan), LECO (US), and DANI Instruments (Italy).

Markets provide quantified B2B research on 30,000 high growth niche opportunities/threats which will impact 70% to 80% of worldwide companies’ revenues. Currently servicing 5000 customers worldwide including 80% of global Fortune 1000 companies as clients. Almost 75,000 top officers across eight industries worldwide approach.The mass spectrometry community is probably the largest group of scientists working around a single tool.  Mass spectrometry (MS), arguably the most important analytical spectroscopic tool of modern times.  There is no single area of experimental science where mass spectroscopy is not being used. There is no university or research institution in the developed world without a mass spectrometer.